When picking or editing a gaming or anime PFP, focus on a clear silhouette and...

https://purepfp.com/why-bold-game-characters-remain-recognisable-in-tiny-profile-icons/

When picking or editing a gaming or anime PFP, focus on a clear silhouette and crop tightly around the face. Keep backgrounds simple to avoid clutter, and skip any text—it usually disappears at small sizes